Family Guy (1999–)

Sick, twisted and politically incorrect, the animated series features the adventures of the Griffin family. Endearingly ignorant Peter and his stay-at-home wife Lois reside in Quahog, R.I., and have three kids. Meg, the eldest child, is a social outcast, and teenage Chris is awkward and clueless when it comes to the opposite sex. The youngest, Stewie, is a genius baby bent on killing his mother and destroying the world. The talking dog, Brian, keeps Stewie in check while sipping martinis and sorting through his own life issues.

Cast: Seth MacFarlane, Alex Borstein, Seth Green